Our research project focuses on the evolution of metal use on Earth, most notably the biochemistry of nitrogen (N) acquisition. We conduct geochemical and biological investigations that involve ancient materials, molecular experiments, and modern natural systems.
What were the abundances and sources of metals involved in N2 fixation on early Earth?
By determining the metal conditions of early Earth and understanding their relevance in ancient environments we can better understand the emergence and evolution of processes required for life, such as nitrogen fixation. This allows us to gain insight into the planet side of “planet-life coevolution” theory on Earth.
What were the biological metal demands of N2 fixation on early Earth?
This initiative aims to better understand the life side of “planet-life coevolution” theory on Earth. Studying the metal requirements of past and present nitrogen fixation biochemistries in vivo and in vitro will help us break down the key incremental steps needed for Earth life element selection.
What were the alternatives to the metals used in N2 fixation?
Here we work to identify the essential metal requirements of past and present nitrogenase as well as potential metal utilization alternatives both in vivo and in silico. This will help us estimate the permissible level of deviation for life to emerge and provide a framework to understand life in other worlds.
Every element contributes uniquely to biochemical functions and has been acted upon by natural selection for eons. Only when we understand those contributions and processes, can we begin to understand the foundation of life on Earth, and how we recognize the potential for life in other worlds.
